How to Optimize Intrathecal Injection Protocols?
Intrathecal (IT) delivery promises direct access to the central nervous system (CNS) by placing a drug into cerebrospinal fluid (CSF), bypassing the blood–brain barrier. That benefit comes with exacting demands on anatomy, dosing precision, and asepsis, especially in small animals where margins for error are slim. The most reliable protocols blend surgical rigor with pharmacokinetic…